长期以来,骨骼肌被认为是一种效应器官,接受神经和体液的调节。近年大量的实验研究发现骨骼肌也具有分泌活性物质的功能,能表达、合成和分泌多种生物信号分子,也是一种重要的内分泌器官。骨骼肌分泌的活性物质以旁分泌或自分泌方式调节骨骼肌的生长、代谢和运动功能,甚至以血液循环的方式调节机体远隔器官组织的功能。 Skeletal muscles have long been considered as effector organs, which are regulated by nerves and body fluids. In recent years, a large number of experimental studies have found that skeletal muscle also has the function of secreting active substances, which can express, synthesize and secrete a variety of biological signal molecules and is also an important endocrine organ. The active substances secreted by skeletal muscle regulate the growth, metabolism and motor function of skeletal muscles in a paracrine or autocrine manner and regulate the function of the distant organ tissues even in the way of blood circulation.