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Stout和Lattes在1967年对软组织恶性纤维细胞瘤(malignant fibrous histoegtoma,MFH)进行了定义。此后,又有几种类型的肉瘤重新分类为MFH。最近的报导中,MFH是软组织肉瘤中最常见的类型。其预后不仅与组织学恶性程度,而且与肿瘤的大小、深浅和发生的部位都密切相关。作者对瑞典南部130万居民1964～1978年已确诊的全部软组织肉瘤(278例)进行了分析,对所有组织学材料进行了重新评价。肿瘤的恶性程度分为4级,其中Ⅳ级恶性程度最高。根据Weiss和Enzinger的
Stout and Lattes defined the malignant fibrous histoegtoma (MFH) in 1967. Since then, several types of sarcomas have been reclassified as MFH. In a recent report, MFH was the most common type of soft tissue sarcoma. The prognosis is not only related to the degree of histological malignancy, but also closely related to the size, depth and location of the tumor. The authors analyzed all soft tissue sarcomas (278 cases) diagnosed from 1300 to 1978 in 1.3 million inhabitants in southern Sweden and re-evaluated all histological materials. The degree of malignancy of the tumor is divided into 4 grades, of which the grade IV malignancy is the highest. According to Weiss and Enzinger