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近20年来,对肝癌的研究有了较快的发展,几乎完全更新了对病因的认识,诊断由较难变为较易,治疗上进入亚临床癌的阶段,基础研究也有所进展。肝癌研究的历史盖伦(Galen)曾有类似肝癌的记述。Hanot 和 Gilbert 对肝癌进行了系统病理分类。angnbuch 于1888年成功的进行肝左叶肿瘤的切除。在病因研究方面1960年开始注意到黄曲霉素,Blumberg 发现了乙型肝炎相关抗原。1960年我国上海生物研究所首先建成第一个人体肝癌细胞群。在肝癌的诊断方面六十年代 B 型超声技术的发展以及核素扫描。肝动脉造影大大提高了定位诊断与影像诊断率。1956年 Bergstrand 发现甲胎蛋白(AFP),
In the past 20 years, the research on liver cancer has developed rapidly, almost completely renewed the understanding of the cause, the diagnosis is more difficult to become easier, the treatment entered the stage of subclinical cancer, and basic research has also progressed. The history of liver cancer research Galen had a similar description of liver cancer. Hanot and Gilbert systematically classified liver cancer. In 1888, angnbuch successfully performed resection of the left lobe tumor. In terms of etiological research, Aflatoxin began to be noticed in 1960, and Blumberg discovered hepatitis B related antigens. In 1960, China’s Shanghai Institute of Biology first built the first human liver cancer cell population. In the diagnosis of liver cancer, the development of B-mode ultrasound technology and radionuclide scans in the 1960s. Hepatic arteriography has greatly improved the diagnostic and imaging diagnostic rates. In 1956 Bergstrand discovered alpha-fetoprotein (AFP),