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目的:研究分析二甲双胍辅助胰岛素降糖治疗糖尿病患者的治疗效果。方法:选择我院从2012年4月~2013年4月收治的糖尿病患者50例,将所有患者随机分为两组,观察组和对照组,每组各25例。在观察组中给予患者二甲双胍以及短、中效预混胰岛素治疗;而对于对照组中的患者采取短、中效预混胰岛素治疗。观察对比两组患者在治疗之后空腹血糖、餐后2h血糖、糖化血红蛋白以及治疗后胰岛素用量的比较。结果:在治疗之后,观察组患者的空腹血糖、餐后2h血糖以及糖化血红蛋白与对照组比较,差异具有统计学意义,P<0.05。观察组患者的胰岛素用量明显低于对照组,两组之间的差异具有统计学意义,P<0.05。结论:对于糖尿病患者在使用注射胰岛素之后血糖控制不满意的时,联合应用二甲双胍辅助治疗具有比较好的治疗效果,值得临床上得到广泛运用。
Objective: To study the effect of metformin-assisted insulin hypoglycemic therapy on diabetic patients. Methods: 50 cases of diabetic patients admitted from April 2012 to April 2013 in our hospital were randomly divided into two groups: observation group and control group, with 25 cases in each group. Patients in the observation group were treated with metformin and short and medium-acting premixed insulin, while patients in the control group were treated with short and medium-acting premixed insulin. The comparison of fasting blood glucose, postprandial blood glucose 2h, glycosylated hemoglobin and insulin after treatment were compared between the two groups. Results: After treatment, the difference of fasting blood glucose, postprandial 2h blood glucose and glycosylated hemoglobin in the observation group was statistically significant (P <0.05). Insulin consumption in the observation group was significantly lower than that in the control group, the difference between the two groups was statistically significant, P <0.05. Conclusions: The combination of metformin adjuvant therapy with diabetic patients with unsatisfactory glycemic control after injecting insulin has a good therapeutic effect and deserves to be widely used clinically.