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据Sun Y 2012年1月27日[Angew Chem Int Ed Engl,2012,51(5):1236-1239]报道,密歇根大学研究人员成功的研制了一个使用液体激光器更好监测轻微的基因突变的方法,这种方法能够提前预防人患特殊类型的肿瘤或者其他疾病。该项研究可以提前识别基因疾病,也可以应用于个性化治疗。在全面的掌握病人的基因信息的基础上进行个性化的靶向药物和其他治疗方法的个性化治疗。研究者认为该技术与现行的方法相比有很大优势,应用荧光染色和其他生物分子学方法查找并且结合到突变的DNA链。当激光巡查到一个突变的基因时,会发射出荧光信号。这看起来似乎是一个坚固的系统,但它不是一个完美的系统。巡查分子倾向于与健康的分子也会结合发出略低于阳性信号的背光
As reported by Sun Y on January 27, 2012 [Angew Chem Int Ed Engl, 2012, 51 (5): 1236-1239], researchers at the University of Michigan have successfully developed a method that uses liquid lasers to better monitor for mild genetic mutations , This method can prevent people suffering from a particular type of cancer or other diseases in advance. The study can identify genetic diseases in advance, can also be applied to personalized treatment. Personalized treatment of personalized targeted drugs and other therapies based on a comprehensive mastery of patient genetic information. The researchers believe this technique offers a significant advantage over the current approach, finding and binding to mutated DNA strands by fluorescent staining and other biomolecular methods. When the laser detects a mutated gene, it emits a fluorescence signal. This may seem like a solid system, but it is not a perfect system. Inspecting molecules tend to combine with healthy molecules to emit a slightly lower-than-positive signal of the backlight