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目的探讨布地奈德联合沙丁胺醇治疗急性小儿支气管哮喘的临床疗效和可行性。方法选取2013年12月—2015年4月大余县人民医院收治的86例支气管哮喘患儿,随机分为研究组和对照组,各43例。研究组给予布地奈德联合沙丁胺醇雾化吸入治疗,对照组单纯给予沙丁胺醇雾化吸入治疗。比较两组患儿临床疗效、不良反应发生情况及复发情况。结果研究组总有效率高于对照组,差异有统计学意义(P<0.05);两组患儿不良反应发生率比较,差异无统计学意义(P>0.05);两组患儿均无复发。结论布地奈德联合沙丁胺醇治疗急性小儿支气管哮喘的临床疗效显著,不良反应少,无复发,可行性好。
Objective To investigate the clinical efficacy and feasibility of budesonide combined with salbutamol in the treatment of acute pediatric bronchial asthma. Methods Totally 86 children with bronchial asthma admitted in Dayu County People’s Hospital from December 2013 to April 2015 were randomly divided into study group and control group, with 43 cases in each group. The study group was given budesonide combined with salbutamol inhalation therapy, the control group was given salbutamol inhalation therapy. The clinical efficacy, adverse reactions and relapse of the two groups were compared. Results The total effective rate of the study group was higher than that of the control group (P <0.05). There was no significant difference in the incidence of adverse reactions between the two groups (P> 0.05). There was no recurrence in both groups . Conclusion Budesonide combined with salbutamol treatment of acute bronchial asthma in children with significant clinical efficacy, fewer adverse reactions, no recurrence, feasibility is good.