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【目的】了解周口市乙肝疫苗应用20年后乙肝病毒表面抗原携带情况,为完善乙肝预防控制措施提供依据。【方法】以周口市1～19岁人群为调查对象,采用酶联免疫吸附试验检测人群中HBsAg携带情况。【结果】周口市调查人群HBsAg阳性率2011年(2.30%)与1999年(7.97%)比下降71.14%,<5岁儿童HBsAg流行率<1%。【结论】乙肝疫苗免疫接种效果显著。做好新生儿乙肝疫苗预防接种,加强中学生及成年人的乙肝疫苗免疫接种。
【Objective】 To understand the situation of HBsAg carrier in Hekou City after 20 years of application, and provide evidence for improving the prevention and control measures of Hepatitis B. 【Methods】 One to 19-year-olds in Zhoukou were enrolled in this study. Enzyme-linked immunosorbent assay (ELISA) was used to detect the presence of HBsAg in the population. 【Results】 The positive rate of HBsAg in the survey population in Zhoukou City dropped 71.14% from 2011 (2.30%) to 1999 (7.97%), and the prevalence rate of HBsAg in children <5 years old was less than 1%. 【Conclusion】 The effect of hepatitis B vaccine immunization is significant. Do neonatal hepatitis B vaccination, to strengthen secondary school and adult hepatitis B vaccine immunization.