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目的:比较盐酸左氧氟沙星与诺氟沙星滴眼液对眼部感染患者致病菌清除率的疗效。方法:选取2014年1月—2015年12月间治疗的眼部感染患者86例,将其随机分为甲组和乙组,每组43例;甲组患者给予盐酸左氧氟沙星滴眼液治疗,乙组患者给予诺氟沙星滴眼液治疗,比较两组患者治疗后细菌清除率及不良反应的发生率。结果:甲组患者治疗后致病菌的清除率高于乙组(P<0.05),两组患者治疗期间均未发生不良反应,且治疗后视力状况与治疗前无差异。结论:采用盐酸左氧氟沙星滴眼液治疗眼部感染患者致病菌的清除率优于诺氟沙星滴眼液的疗效,不良反应小,安全有效。
OBJECTIVE: To compare the efficacy of levofloxacin hydrochloride and norfloxacin eye drops in the clearance of pathogenic bacteria in patients with ocular infection. Methods: Eighty-six patients with ocular infections were selected from January 2014 to December 2015. They were randomly divided into group A and group B, 43 cases in each group. Patients in group A were treated with levofloxacin hydrochloride eye drops, The patients were treated with norfloxacin eye drops. The bacterial clearance rate and the incidence of adverse reactions were compared between the two groups after treatment. Results: The clearance rate of pathogens in group A was higher than that in group B (P <0.05). There was no adverse reaction during the treatment in both groups, and there was no difference in visual acuity after treatment. Conclusion: Levofloxacin Hydrochloride Eye Drops is superior to norfloxacin eye drops in the treatment of ocular infection. The adverse reaction is safe and effective.