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目的探讨慢性呼吸衰竭(CRF)患者酸碱失衡状况和预后的关系。方法收集本院2011年6月~2013年6月108例慢性呼吸衰竭住院患者,抽血进行酸碱分析并给予改善通气、加强营养支持、必要的抗感染及呼吸机辅助通气等治疗,观察其治疗效果及并发症发生。结果本研究中,单纯酸碱失衡CRF患者63例治疗有效率高达95.2%,二重酸碱失衡CRF患者34例治疗有效率为17.6%,而三重酸碱失衡CRF患者11例治疗均无效死亡。相对于二重以上酸碱失衡CRF患者,单纯酸碱失衡CRF患者并发症发生率较低,其持续发热、神志不清、心律失常、休克及肾功能衰竭等并发症发生率分别为9.5%、6.3%、12.7%、0、4.8%。结论本研究表明CRF患者酸碱失衡状况对于CRF治疗预后具有一定的提示意义,可以为临床治疗提供参考。
Objective To investigate the relationship between acid-base imbalance and prognosis in patients with chronic respiratory failure (CRF). Methods A total of 108 hospitalized patients with chronic respiratory failure were collected from June 2011 to June 2013 in our hospital. Blood and acid-base analysis was performed to improve the ventilation, nutrition support, necessary anti-infection and ventilator-assisted ventilation. Therapeutic effects and complications. Results In this study, 63 cases of simple acid-base imbalance CRF treatment efficiency was as high as 95.2%, 34 cases of double acid-base imbalance CRF treatment effective rate was 17.6%, and triple acid-base CRF patients 11 cases were ineffective treatment of death. Relative to patients with CRF more than double in acid-base balance, simple complication of acid-base imbalance CRF patients with low incidence of persistent fever, confusion, arrhythmia, complications such as shock and renal failure rates were 9.5% 6.3%, 12.7%, 0,4.8%. Conclusion This study shows that the acid-base imbalance status of patients with CRF has some implications for the prognosis of CRF, which may provide a reference for clinical treatment.