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据82年第5期日经医学报道:类固醇制剂从来是用于抑制免疫反应和控制炎症的。而对乙型肝炎的中断疗法是集中投与类固醇后一旦中断,引起较强的免疫反应,从而促进乙肝病毒抗体的出现,人为地引起血清转换(seroconversion)这种免疫现象。东京虎之门病院熊田博光氏在最近召开的日本消化器病学会讨论会上发表了该院HBs用性1年以上132例慢性肝炎的观察结果。方法是首次给强地松龙40mg(6～7mg/kg)以后渐减,待HBs抗原效价2~7～2~(10)。较低时停药。由于短期集中给与类固醇,一旦引起较强的免疫反应抑制后,因抑制的解放,相反引起更强的免疫反应,人为地达到血清转换。10例e抗原
According to the 82nd issue of the 5th Nikkei Medical reported: steroid preparations have been used to suppress the immune response and control inflammation. The interruption of hepatitis B therapy is concentrated steroid administered once interrupted, causing a strong immune response, thereby promoting the emergence of hepatitis B virus antibodies, artificially causing seroconversion (seroconversion) of this immune phenomenon. Tokyo Toranomon Hospital Kumada Hirobumi held a meeting of the Japan Society of Digestive Diseases at a recent symposium in which 132 cases of chronic hepatitis with an age of 1 year or more were used. Method for the first time to prednisolone 40mg (6 ~ 7mg / kg) after the gradual decrease until the HBs antigen titer 2 ~ 7 ~ 2 ~ (10). Lower withdrawal. Due to the short-term concentrated administration of steroids, once the strong immune response is inhibited, due to the inhibition of the liberation, on the contrary caused a stronger immune response, artificially achieve seroconversion. 10 cases of e antigen