论文部分内容阅读
目的:探讨抗生素规范管理对控制神经内科住院患者医院感染的作用。方法:对我院神经内科2008年6月～2011年6月226例住院患者分为二组,2009年12月抗生素规范管理前的101例患者为对照组,2010年1月～2011年6月抗生素规范管理后的125例患者为观察组,对二组用药情况及医院感染患者情况进行综合分析。结果:对照组患者中81例使用抗生素,其中治疗性使用32例,占39.51%,预防性使用49例,占60.49%;发生医院感染14例,占13.86%;2010年1月通过一系列抗生素规范管理的相关措施的实施,观察组患者中54例使用抗生素,占43.2%,其中治疗性使用39例,占72.22%,预防性使用15例,占27.78%;发生医院感染感染11例,占8.8%;二组患者前后抗生素使用量比较差异明显,有统计学意义P<0.05,二组医院感染率差异不明显,无统计学意义P>0.05。结论:预防使用抗生素应有针对性,无目的的预防使用抗生素不能控制医院感染,因此,加强对抗生素的规范管理,有利于抗生素的合理使用,避免耐药菌的产生。
Objective: To investigate the role of standard management of antibiotics in controlling nosocomial infections in inpatients with neurology. Methods: 226 cases of inpatients in our hospital from June 2008 to June 2011 were divided into two groups. In December 2009, 101 patients before the standardized management of antibiotics were the control group. From January 2010 to June 2011 A total of 125 patients under the standardized management of antibiotics were observed, and a comprehensive analysis was conducted on the use of the two drugs and the patients with nosocomial infections. Results: The control group of 81 patients with antibiotics, including the use of 32 cases of treatment, accounting for 39.51%, 49 cases of prophylactic use, accounting for 60.49%; hospital infection occurred in 14 cases, accounting for 13.86%; in January 2010 through a series of antibiotics 54 cases of antibiotics were observed in the observation group, accounting for 43.2%, of which 39 cases were used therapeutically, accounting for 72.22%, 15 cases were preventive use, accounting for 27.78%; 11 cases of nosocomial infection occurred, accounting for 8.8%. There was significant difference in antibiotics usage before and after the two groups, with statistical significance (P <0.05). There was no significant difference in nosocomial infection rate between the two groups (P> 0.05). Conclusion: Prevention of the use of antibiotics should be targeted, purposeless prevention of antibiotics can not control nosocomial infections, therefore, to strengthen the standard management of antibiotics is conducive to the rational use of antibiotics to prevent the generation of resistant bacteria.