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目的:观察激素、骁悉及中药联合用药治疗难治性肾病综合征的临床疗效。方法:将难治性肾病综合征患者16例,给予强的松、骁悉口服,并据激素使用的不同阶段配合中药辨证治疗,观察治疗前后临床症状、体征、血清白蛋白、尿蛋白、胆固醇、甘油三酯等指标,综合评定疗效。结果:总有效率为93.75％,达到基本缓解的平均时间为21天,1年复发率为12.5％。结论:以激素、骁悉及中药联合用药治疗难治性肾病综合征有明显疗效。
Objective: To observe the clinical effects of combined hormones, Xiao-xi and traditional Chinese medicine in the treatment of refractory nephrotic syndrome. Methods: Sixteen patients with refractory nephrotic syndrome were given prednisone and XiaoXitian orally. According to the different stages of hormone use, the symptoms and signs, serum albumin, urine protein, cholesterol , Triglycerides and other indicators, a comprehensive assessment of efficacy. Results: The total effective rate was 93.75%. The average time to achieve basic remission was 21 days. The recurrence rate at 1 year was 12.5%. Conclusion: The treatment of refractory nephrotic syndrome with hormones, Xiao-xi and traditional Chinese medicine has obvious curative effect.