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肺炎衣原体是常见的呼吸道感染病原体。近年来研究发现动脉粥样硬化患者中衣原体抗体检出率高,免疫复合物亦高于对照组。在动脉硬化病变处常发现有梨状肺炎衣原体存在。衣原体感染人体后可通过其脂多糖及与抗体形成的免疫复合物,作用于血管内皮细胞、吞噬细胞、血小板、红细胞等,产生细胞因子,影响脂代谢、凝血系统等,促进动脉硬化的发生发展。
Chlamydia pneumoniae is a common pathogen of respiratory infections. In recent years, the study found that patients with atherosclerosis detection rate of chlamydia antibodies, immune complexes also higher than the control group. In atherosclerotic lesions often found in the presence of C. pneumoniae Chlamydia. Chlamydial infection of the human body through its lipopolysaccharide and antibodies with immune complexes formed on the role of vascular endothelial cells, phagocytic cells, platelets, red blood cells, etc., produce cytokines, affecting lipid metabolism, coagulation system, and promote the development of atherosclerosis .