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本文报告了以羧甲基纤维素钠作牙周缓释剂局部应用治疗牙周病149例,效果良好。以羧甲基纤维素钠作为缓释剂载体材料,局部释放螺旋霉素治疗牙周病。使药物直接作用于牙周破坏部位,具有用药量小、局部浓度高,无副作用,而且缓释剂载体材料具有能被唾液、龈沟液、血液等溶解而缓慢、持久地释放药物,使局部维持有效药物浓度时间较长,有利于杀菌;以及取材、制作、使用方便等优点。
This article reports the use of sodium carboxymethyl cellulose as periodontal sustained-release agent for the treatment of periodontal disease in 149 cases, the effect is good. Sodium carboxymethyl cellulose as a sustained release carrier material, the local release of spiramycin treatment of periodontal disease. So that drugs directly on the role of periodontal destruction sites, with a small dose, high local concentration, no side effects, and sustained release carrier material can be dissolved by saliva, gingival crevicular fluid, blood and slow, sustained release of drugs, the local Maintaining effective drug concentration for a long time is conducive to sterilization; and drawn, production, easy to use and so on.