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应用逆转录－聚合酶链反应（ＲＴ－ＰＣＲ）和限制性片段长度多态性（ＲＦＬＰ）技术分析安徽省丙肝患者丙型肝炎病毒（ＨＣＶ）基因型。结果表明ＨＣＶ基因型有Ⅰ、Ⅱ、Ⅲ、Ⅳ及Ⅱ／Ⅲ混合型，以Ⅱ型感染（７５．６６％）占优势，其次为Ⅲ型（１３．２３％）和Ⅱ／Ⅲ型（６．３５％），Ⅰ、Ⅳ型各有１例（０．５３％）。安徽省北部地区的ＨＣＶⅢ型多于南部，而Ⅱ型北部则少于南部，不同地理区域ＨＣＶ基因型分布差异有显著性（Ｐ＜０．０５）。有、无输血、血液制品史的丙肝患者间ＨＣＶ基因型分布差异无显著性
Hepatitis C virus (HCV) genotypes in hepatitis C patients in Anhui Province were analyzed by reverse transcription-polymerase chain reaction (RT-PCR) and restriction fragment length polymorphism (RFLP). The results showed that the genotypes of HCV were mixed type Ⅰ, Ⅱ, Ⅲ, Ⅳ and Ⅱ / Ⅲ, with type Ⅱ infection (75.66%) predominant, followed by type Ⅲ (13.23%) and type Ⅱ / Ⅲ .35%), each of type Ⅰ and type Ⅳ had one case (0.53%). There were more HCVⅢs in the northern part of Anhui province than in the southern part, but less in the northern part of Ⅱ, while the distribution of HCV genotypes in different geographical regions was significantly different (P <0.05). There was no significant difference in the distribution of HCV genotype between hepatitis C patients with or without blood transfusion and blood products history