We report a general and highly efficient Mukaiyama-aldol reaction of ketones and difluoroenoxysilanes.While the reaction of aryl ketones worked efficiently in the presence of Bi(OTf)_3, that of aliphatic ketones required the use of Sc(OTf_)3. In addition, Sc(OTf)_3 was capable of achieving excellent 1,2-selectivity in the corresponding reaction of α,β-unsaturated ketones. This method provides a facile access to differently substituted β-hydroxy α,α-difluoro ketones, versatile synthons for difluomethylated tertiary alcohols. We report a general and highly efficient Mukaiyama-aldol reaction of ketones and difluoroenoxysilanes. Whilst the reaction of aryl ketones was efficiently in the presence of Bi (OTf) _3, that of aliphatic ketones required the use of Sc (OTf_) 3. , Sc (OTf) _3 was capable of achieving excellent 1,2-selectivity in the corresponding reaction of α, β-unsaturated ketones. This method provides a facile access to differently substituted β-hydroxy α, α- difluoro ketones, versatile synthons for difluomethylated tertiary alcohols.