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应用免疫组化方法对90例良性乳腺病变组织进行ER、PR的检测。结果:ER阳性率为84.4%,PR为83.3%,与同期乳腺癌的ER和PR阳性率相比较有非常显著性意义。ER阳性以纤维腺瘤、导管内乳头状瘤、囊性乳腺增生症最为常见,小叶内增生ER阳性相对减少。同时对乳腺组织间质中存在有背景染色问题加以讨论。
The immunohistochemical method was used to detect ER and PR in 90 benign breast lesions. Results: The positive rate of ER was 84.4% and the PR was 83.3%. It was very significant compared with the positive rate of ER and PR in breast cancer during the same period. Fibroblast adenomas, intraductal papillomas, and cystic hyperplasia were the most common ER-positive lesions, and ER-positive lobular hyperplasia was relatively reduced. At the same time, the background staining of mammary tissue is discussed.