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目的 探讨血浆和房水内皮素 1(ET 1) ,白细胞介素 8(IL 8)与人工晶状体植入术后炎性并发症关系。方法 对 40例晶状体囊外摘出后房型人工晶状体植入术后 3种不同级别炎性并发症家兔进行血浆和房水ET 1,IL 8测定 ,检测方法为放射免疫测定。结果 40只家兔ET 1,IL 8术后在血浆和房水内较术前均升高 ,且与术后炎性并发症呈正相关。结论 检测血浆和房水中ET 1、IL 8水平可作为监测术后恢复情况 ,估计预后及转归的实验室指标
Objective To investigate the relationship between plasma and aqueous endothelin 1 (ET 1), interleukin 8 (IL 8) and inflammatory complications after intraocular lens implantation. Methods Plasma and aqueous humor ET 1 and IL 8 levels in 40 rabbits with inflammatory complications of extracapsular lens extraction after posterior chamber intraocular lens implantation were measured. The detection method was radioimmunoassay. Results The plasma and aqueous humor levels of ET 1 and IL 8 in 40 rabbits were all higher than those before operation, and were positively correlated with postoperative inflammatory complications. Conclusion The detection of ET 1 and IL 8 levels in plasma and aqueous humor can be used as a laboratory index to monitor postoperative recovery, prognosis and prognosis