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GUSTO研究,即国际急性心肌梗塞四种溶栓方案随机试验研究,心肌梗塞的发病时间不超过6h。目的是比较4种不同治疗方法的治疗效果。1.静脉注射链激酶150万IU1h,肝素12500IU皮 下注射每日二次。2.静脉滴注链激酶150万IU1h,接着静脉注射肝 素5000IU,再滴注肝素1000～1200IU/h。3.大剂量t-PA。首先t-PA15mg静脉注射,随后 0.75mg/kg静脉滴注30min,0.5mg/kg静脉滴 注60min,直至总剂量达到100mg。肝素静脉注射 和滴注同上述链激酶的治疗方法。
GUSTO study, the international acute myocardial infarction four thrombolytic protocols randomized study, the incidence of myocardial infarction time does not exceed 6h. The purpose is to compare the therapeutic effects of 4 different treatments. 1. Intravenous streptokinase 1.5 million IU1h, heparin 12500IU subcutaneous injection twice daily. 2. Intravenous streptokinase 1.5 million IU1h, followed by intravenous injection of heparin 5000IU, and then drip heparin 1000 ~ 1200IU / h. 3. High-dose t-PA. First t-PA15mg intravenous injection, followed by 0.75mg / kg intravenous infusion of 30min, 0.5mg / kg intravenous infusion of 60min, until the total dose of 100mg. Heparin intravenous infusion and infusion with the above streptokinase treatment.