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目的观察坤泰胶囊治疗特发性卵巢早衰的临床疗效。方法将60例特发性卵巢早衰患者随机分为两组,各30例;治疗组给予坤泰胶囊联合周期性激素替代治疗,对照组给予周期性激素替代治疗,疗程3个月。结果治疗3个月后两组临床疗效无显著性差异(P>0.05);6个月后随访,治疗组复发率为16.67%,对照组为63.33%;治疗组复发率低于对照组(P<0.01)。治疗后两组血清FSH和LH水平明显降低(P<0.01),E2水平升高(P<0.01);两组E2、FSH、LH水平比较差异有统计学意义(P<0.01)。结论坤泰胶囊可改善特发性卵巢早衰患者的卵巢功能。
Objective To observe the curative effect of kuntai capsule on idiopathic premature ovarian failure. Methods Sixty patients with idiopathic premature ovarian failure were randomly divided into two groups, 30 cases in each. The treatment group was treated with kuntai capsule combined with periodic hormone replacement therapy and the control group with periodic hormone replacement therapy. The treatment course was 3 months. Results After 3 months of treatment, there was no significant difference between the two groups (P> 0.05). After 6 months follow-up, the recurrence rate was 16.67% in the treatment group and 63.33% in the control group. The recurrence rate in the treatment group was lower than that in the control group <0.01). Serum levels of FSH and LH were significantly decreased (P <0.01) and E2 levels were increased after treatment in both groups (P <0.01). The levels of E2, FSH and LH in the two groups were significantly different (P <0.01). Conclusions Kun Tai Capsule can improve ovarian function in patients with idiopathic premature ovarian failure.