真正的牙周病原菌是什么至今尚不明确.由于龈沟液较能敏感地反映牙周局部的炎症状态,作者等探讨了用检测龈沟液中炎症介质的方法来评价牙周病原菌的可能性。材料和方法检查了53名19～60岁的边缘性牙周炎患者,牙周袋深度为2～11mm的171个部位.这些受检者以往未患过全身病,近1年内未接受过牙周治疗.每个部位同时测以下各项:①龈炎指数,菌斑指数,骨吸收率等临床参数并评分;②龈下菌斑采样,在细菌计 The true periodontal pathogens what is not yet clear.As the gingival crevicular fluid is more sensitive to reflect the local periodontal inflammatory state, the authors discussed the use of methods to detect inflammatory media in gingival crevicular fluid to evaluate the possibility of periodontal pathogens . MATERIALS AND METHODS Fifty-three marginal periodontitis patients 19 to 60 years of age were examined at 171 sites with a periodontal pocket depth of 2 to 11 mm that had not previously had any systemic disease and had not had teeth in the past year Week treatment.At the same time, each site measured the following: ① gingivitis index, plaque index, bone resorption rate and other clinical parameters and score; ② subgingival plaque sampling, bacteria in the meter