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目的:比较泛昔洛韦与阿昔洛韦治疗带状疱疹的临床效果。方法:回顾性分析60例带状疱疹患者的临床资料,将其随机分为观察组与对照组,每组各30例,其中对照组采用阿昔洛韦进行治疗,观察组则采用泛昔洛韦进行治疗,比较两组患者症状消失、急性神经痛持续时间及临床总有效率。结果:观察组患者的止疱时间、结痂时间、脱痂时间、缓解疼痛时间及持续急性神经痛时间均显著短于对照组(P<0.05)。两组患者的临床总有效率差异无统计学意义(P>0.05);两组患者的临床总有效率差异不显著(P>0.05)。结论:带状疱疹患者治疗中泛昔洛韦与阿昔洛韦的临床治疗效果相当,但泛昔洛韦见效快,可显著缩短带状疱疹各种症状改善时间,抑制持续急性神经痛,安全、有效,可作为带状疱疹治疗的首选药物。
Objective: To compare the clinical efficacy of famciclovir and acyclovir in the treatment of shingles. Methods: The clinical data of 60 patients with shingles were retrospectively analyzed. They were randomly divided into observation group and control group, with 30 cases in each group. The control group was treated with acyclovir, and the observation group was treated with famciclovir The symptoms disappeared, the duration of acute neuralgia and the total clinical effective rate were compared between the two groups. Results: The blistering time, scabbing time, scabbing time, pain relief time and persistent pain time in observation group were significantly shorter than those in control group (P <0.05). There was no significant difference in the total effective rate between the two groups (P> 0.05). There was no significant difference in the total effective rate between the two groups (P> 0.05). Conclusions: The clinical treatment of famciclovir and acyclovir in patients with shingles is quite effective, but famciclovir is effective. It can significantly shorten the time to improve various symptoms of shingles, inhibit the persistent acute neuralgia, and be safe and effective. Herpes drug treatment of choice.