HI-6是属双季胺单肟类化合物。其结构式如下。这类化合物能对抗梭曼及沙林中毒,主要作用可能是对中毒酶的重活化。我们也曾提及HI-6是8个重活化剂中最强的一个。它既然能重活化组织中被抑制了的胆碱酯酶(GhE),那么,能否恢复组织器官被梭曼阻抑了的功能呢?79年的工作中见到大鼠梭曼膈肌局部中毒后终板新生的ChE与功能的恢复较密切相关,重活化的ChE与功能间的关系又如何呢?为了回答这些问题而进行本研究。 HI-6 is a double quaternary ammonium mono-oxime compounds. Its structure is as follows. Such compounds can fight soman and sarin poisoning, the main role may be the reactivation of toxins. We also mentioned that HI-6 is the strongest of the eight heavy activators. Since it can reactivate the inhibited cholinesterase (GhE) in the tissue, can it restore the function of the tissues and organs that is blocked by soman? Localized poisoning of the soman membrane in the rat for 79 years The post-platelet ChE is more closely related to functional recovery, and what is the relationship between reactivated ChE and function? To answer these questions, we conducted this study.