女,5月。因患“上感”后出现颜面浮肿、腹胀2月入院。平日消化力差,进食后易呕吐,腹泻。生后头小、少动。出生体重2.5kg。父母非近亲婚配。体检:体重5kg,头围33cm。发育迟缓,智力低下,小头尖顶,囱门已闭,颅缝重叠,额狭,枕部平坦,脸及耳朵相对较大,两服睑明显肿胀,周身凹陷性水肿,心肺无殊。腹胀,腹壁静脉显露,有移动性浊音,拇指内收至掌心。化验:肝功能及HBsAg、Bun正 Female, May. Due to suffering “feeling ” after facial puffiness, bloating admitted in February. Poor digestion weekdays, easy to vomit after eating, diarrhea. After a small head, less moving. Birth weight 2.5kg. Parents non-relatives marriage. Physical examination: weight 5kg, head circumference 33cm. Stunted, mental retardation, small spire, closed fissure, cranial suture overlap, the amount of narrow, flat occipital, face and ears are relatively large, two eyelids were swollen, depressed edema, no cardiopulmonary. Abdominal distension, ventral veins revealed, shifting dullness, the thumb closed to the palm. Laboratory tests: liver function and HBsAg, Bun positive