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目的对一起中心静脉置管后菌血症暴发感染进行调查分析,探讨防治措施,为预防和控制医院感染提供参考依据。方法对肿瘤内科4例患者在2008年8月4日~8日期间因中心静脉置管后菌血症暴发流行进行调查分析。结果4例患者血培养、中心静脉导管尖端和治疗室台面等均分离出产酸克雷伯菌,且药物菌谱完全一致。结论此次产酸克雷伯菌引起的菌血症为局部暴发流行。部分人员无菌观念淡薄、无菌操作执行不严可能是引起此次感染的主要原因。提示中心静脉置管者,一旦出现不明原因的感染症状,应考虑中心静脉置管因素。
Objective To investigate and analyze the outbreak of bacteremia after central venous catheterization and to explore the prevention and control measures to provide a reference for the prevention and control of nosocomial infections. Methods Four patients with oncology were enrolled in this study. The outbreaks of bacteremia after central venous catheterization were investigated during the period from August 4 to August 8, 2008. Results Blood cultures, central venous catheter tips and treatment room tabletops were all isolated from 4 patients with Klebsiella oxytoca. The spectrum of drug was identical. Conclusion The bacteremia caused by Klebsiella oxytoca is a local outbreak. Some staff sterile concept of weak, lax aseptic implementation may be the main cause of the infection. Tip central venous catheterization, in the event of an unexplained infection symptoms, should consider the central venous catheter factors.