论文部分内容阅读
作者用体外反搏器治疗脑动脉供血不足疾病,是在治疗冠状动脉供血不足疾病基础上的发展。本文在11只狗上观察了体外反搏对颈总动脉血流量和脑血管的影响,并对20例脑动脉供血不足疾病,进行了体外反搏疗效的初步观察。动物实验结果表明,体外反搏使狗的颈总动脉血流量增加75%以上,外局阻力减少,脑血管造影显示,颅内血管侧支、吻合支开放明显增加。临床观察结果,10/12例脑动脉硬化患者,头痛、眩晕症状消失或明显减轻,大脑记忆功能和反应速度得到提高,部分脑阻抗血流图有不同程度改善;5/8例帕金森氏症有较大改善。体外反搏为治疗脑动脉供血不足疾病,提供一条新的治疗途径。体外反搏,是利用循环机械辅助装置在心舒张期压迫肢体,提高主动脉舒张压,从而增加冠状动脉灌流量。实验证明,它不仅能减轻心脏负荷,增加心排出量,而且在心肌耗氧量略有下降情况下,增加心室功率和心脏指数,使心脏功能获得显著改善。国内在治疗心肌梗塞和冠心病中,也取得一定的疗效。由于颈总动脉是主动脉弓的主要分支,体外反搏能否增加颈总动脉血流量,改善脑循环?国内外尚未见类似报道。为了探索这些问题,作者观察体外反搏对狗颈总动脉血流量和脑血管的变化,并对脑动脉硬化症和帕金森氏症患者,进行了初步疗效观察。
The authors use in vitro pacemaker treatment of cerebral arterial insufficiency disease is in the treatment of coronary insufficiency based on the development of the disease. In this paper, we observed the effects of EECP on the common carotid artery blood flow and cerebrovascular in 11 dogs and made a preliminary observation on the efficacy of external counterpulsation in 20 cases of cerebral arterial insufficiency. Animal experiments show that extracorporeal counterpulsation increases the common carotid artery blood flow in dogs by more than 75% and the external resistance decreases. Cerebral angiography shows that the intracranial vascular collaterals and anastomotic branches are significantly increased. Clinical observations showed that 10/12 cerebral arteriosclerosis patients had no or significant headache and vertigo symptoms, improved brain memory function and response rate, and improved partial cerebral impedance blood flow maps to varying degrees. In 5 of 8 patients with Parkinson’s disease There is a big improvement. Extracorporeal counterpulsation for the treatment of cerebral arterial insufficiency disease, providing a new therapeutic approach. Extracorporeal counterpulsation, is the use of circulatory assistance devices in the diastolic limb compression, improve aortic diastolic blood pressure, thereby increasing coronary perfusion. Experiments show that it can not only reduce the heart load, increase cardiac output, and myocardial oxygen consumption decreased slightly in the case of increased ventricular power and cardiac index, the heart function improved significantly. In the treatment of myocardial infarction and coronary heart disease, but also achieved some results. As the common carotid artery is the main branch of the aortic arch, whether external counterpulsation can increase the common carotid artery blood flow and improve the cerebral circulation? No similar reports at home and abroad. In order to explore these issues, the authors observed the changes in dog’s common carotid artery blood flow and cerebrovascular by extra-corporeal counterpulsation, and observed the initial curative effect on patients with cerebral arteriosclerosis and Parkinson’s disease.