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目的:观察注射用丹参多酚酸盐联合左卡尼汀注射液治疗老年(≥65岁)稳定型心绞痛的疗效。方法:回顾性分析120例老年稳定型心绞痛患者的临床资料。对照组60例给予阿司匹林、硝酸酯类、钙拮抗剂及β-受体阻滞剂等常规治疗;观察组60例在常规治疗基础上应用注射用丹参多酚酸盐联合左卡尼汀注射液,比较2组患者治疗后的临床症状和心电图改善情况。结果:观察组临床症状改善总有效率为90.0%,明显高于对照组的63.3%(P<0.01);观察组心电图改善总有效率为86.7%,显著高于对照组的53.3%(P<0.01)。2组均未发现明显不良反应。结论:注射用丹参多酚酸盐联合左卡尼汀注射液治疗老年稳定型心绞痛能有效缓解患者临床症状,改善缺血心电图,值得临床进一步推广使用。
Objective: To observe the efficacy of Salviae miltiorrhizae for injection in combination with L-carnitine injection in the treatment of elderly patients (≥65 years) with stable angina pectoris. Methods: The clinical data of 120 elderly patients with stable angina pectoris were retrospectively analyzed. Control group 60 patients given aspirin, nitrates, calcium antagonists and β-blockers and other conventional treatment; observation group of 60 patients on the basis of routine treatment with Salviae miltiorrhizae for injection in combination with levocarnitine injection The clinical symptoms and electrocardiogram improvement were compared between the two groups after treatment. Results: The total effective rate of clinical symptom improvement in observation group was 90.0%, significantly higher than 63.3% in control group (P <0.01). The total effective rate of electrocardiogram improvement in observation group was 86.7%, which was significantly higher than that in control group (53.3%, P < 0.01). No significant adverse reactions were found in both groups. Conclusion: Salviae miltiorrhizae injection combined with levocarnitine injection for the treatment of elderly patients with stable angina pectoris can effectively alleviate the clinical symptoms and improve the ischemic electrocardiogram, which is worth further promotion in clinic.