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目的探讨亚急性甲状腺炎的临床表现、诊断和治疗。方法对1998年1月～2008年1月本院病房收治的42例亚急性甲状腺炎进行回顾性分析。结果在42例患者中,女性多见,30～50岁占78.6%,颈部前疼痛(88.1%)和甲状腺触痛(92.9%)是主要的临床表现;所有病例C反应蛋白和血沉升高,24例(57.1%)血促甲状腺激素水平降低,41例(97.6%)甲状腺核素显影模糊或无显影;所有患者予强的松或消炎痛治疗,予消炎痛治疗者2～7d颈部疼痛明显好转,予强的松治疗者1～3d颈部疼痛明显好转,予以消炎痛治疗后颈部疼痛无好转者改用强的松可使颈部疼痛明显好转。结论多数亚急性甲状腺炎有典型的临床表现,结合血沉、甲状腺功能和甲状腺核素扫描等辅助检查可明确诊断;强的松和消炎痛对亚急性甲状腺炎均有确切疗效,其中强的松比消炎痛能更快、更好地缓解疼痛。
Objective To investigate the clinical manifestations, diagnosis and treatment of subacute thyroiditis. Methods A retrospective analysis was performed on 42 cases of subacute thyroiditis admitted to our ward from January 1998 to January 2008. Results Among the 42 patients, women were more common, accounting for 78.6% of the patients aged 30-50 years. Pre-neck pain (88.1%) and thyroid tenderness (92.9%) were the main clinical manifestations. C-reactive protein and erythrocyte sedimentation rate , 24 cases (57.1%) reduced serum thyroid hormone level, 41 cases (97.6%) thyroid nuclide developed fuzzy or no imaging; all patients were treated with prednisone or indomethacin, indomethacin treatment for 2 ~ 7d neck Significant improvement in pain, to prednisone treatment 1 ~ 3d neck pain was significantly improved, to indomethacin treatment of neck pain without improvement after the switch to prednisone neck pain significantly improved. Conclusions Most subacute thyroiditis has the typical clinical manifestations, which can confirm the diagnosis with the assistant examination such as ESR, thyroid function and thyroid radionuclide scan. Prednisone and indomethacin have definite curative effect on subacute thyroiditis. The prednisone ratio Indomethacin can relieve pain faster and better.