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目的:观察育龄期功能性子宫出血患者宫腔放置曼月乐及口服妈富隆的疗效。方法:选取育龄期功能性子宫出血患者72例,分为曼月乐组31例和妈富隆组41例,比较治疗后6个月及12个月的有效率及子宫内膜厚度。结果:治疗后6个月妈富隆组的有效率与曼月乐组比较差异无统计学意义(P>0.05);12个月后曼月乐组的有效率高于妈富隆组(P<0.05)。治疗后6个月及12个月两组子宫内膜厚度均较同组治疗前变薄(P<0.05);治疗后6个月两组间子宫内膜厚度差异无统计学意义(P>0.05),12个月后曼月乐组较妈富隆组子宫内膜明显变薄(P<0.05)。结论:曼月乐治疗育龄期功能性子宫出血的长期疗效优于妈富隆,值得在经济条件允许的患者中推广使用。
Objective: To observe the efficacy of placing Mirena and oral Marvelon in the uterine cavity of functional uterine bleeding patients of childbearing age. Methods: Seventy-two patients with functional uterine bleeding during childbearing age were selected and divided into three groups: 31 cases in Mirena group and 41 cases in Marvelon group. Efficacy and endometrial thickness at 6 months and 12 months after treatment were compared. Results: Six months after treatment, the effective rate of Marvelon group was not significantly different from that of Mirena group (P> 0.05). The effective rate of Mirena group after 12 months was higher than that of Marvelon group (P <0.05) ). After 6 months and 12 months, the thickness of endometrium in both groups was thinner than that in the same group before treatment (P <0.05). There was no significant difference in endometrial thickness between the two groups after 6 months of treatment (P> 0.05 ). After 12 months, the Mirena group was significantly thinner than the Marvelon group (P <0.05). Conclusion: The long-term curative effect of Mirena therapy on functional uterine bleeding in childbearing age is better than that of Marvelon, which is worth popularizing in patients with economic conditions.