抗凝血酶Ⅲ(ATⅢ)是肝脏制造的丝氨酸蛋白酶抑制剂,肝功能不全时其含量常不足。本文报道ATⅢ治疗暴发性肝衰竭(FHF)的疗效。对象及方法:受试对象为26例急性(发病后10天内出现脑病)或亚急性(10天以上)FHF患者,于急性肝炎后8周均发生二级以上肝昏迷,前凝血酶时间降至正 Antithrombin Ⅲ (AT Ⅲ) is a serine protease inhibitor made by the liver, its content is often not enough when liver dysfunction. This article reports the efficacy of AT III in the treatment of fulminant hepatic failure (FHF). PARTICIPANTS AND METHODS: Twenty-six patients with acute FHF (encephalopathy within 10 days after onset) or subacute (over 10 days) were enrolled in this study. Hepatic coma more than grade 2 occurred at 8 weeks after acute hepatitis, and the prothrombin time was reduced to positive