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免疫球蛋白作为免疫调节剂静脉输注已用于治疗特发性血小板减少紫瘢。免疫性白细胞减少症,重症肌无力、川畸病、纯抗体介导的红细胞发育不全症和抗遗传型自身抗体产生。本文作者报道静脉输注大剂量人类γ-球蛋白治疗人类特发性膜性肾病。病人和方法:9例病人均经肾活检诊断为膜性肾病,并排除系统性红斑狼疮、糖尿病、淀粉样变、药瘾或慢性肝病等所引起的继发性膜性肾病。5例肾功能正常Ccr125.2±16ml/min/1.73m2(A组),4例中度肾功能不全Ccr65.5±8.3ml/min/1.73m2(B
Intravenous immunoglobulin as an immunomodulatory agent has been used to treat idiopathic thrombocytopenic purpura. Autoimmune leukopenia, myasthenia gravis, Kawasaki disease, pure antibody-mediated erythroid hypoplasia and anti-idiotypic autoantibodies. The authors report that intravenous infusion of large doses of human gamma-globulin in the treatment of idiopathic membranous nephropathy. Patients and Methods: All 9 patients were diagnosed as membranous nephropathy by renal biopsy and excluded secondary membranous nephropathy caused by systemic lupus erythematosus, diabetes mellitus, amyloidosis, drug addiction or chronic liver disease. 5 cases of normal renal function Ccr125.2 ± 16ml / min / 1.73m2 (A group), 4 cases of moderate renal insufficiency Ccr65.5 ± 8.3ml / min / 1.73m2 (B