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目的:采用血清标志物作为检查手段来了解胎盘功能及胎儿发育情况。方法:采用放免法测定血清雌二醇(E2)、游离雌三醇(E3)、孕酮(P)、胎盘催乳素(HPL);采用单项免疫扩散法测定妊娠特异性β1糖蛋白(SP1)。结果:中、晚期妊娠妇女正常组与异常组血清E2、E3、P、HPL结果差异无显著性(P<0.05),妊高组中45.45%SP1低值。正常组中无一例SP1低值。结论:常规检测中、晚期妊娠妇女血SP1值,具有重要的临床意义。
Objective: To use serum markers as a means of examination to understand placental function and fetal development. Methods: Serum estradiol (E2), free estriol (E3), progesterone (P) and placental prolactin (HPL) were determined by radioimmunoassay. Pregnancy-specific β1 glycoprotein . Results: The results of serum E2, E3, P and HPL in normal and abnormal pregnant women were not significantly different (P <0.05), and 45.45% of SP1 in pregnant women with high pregnancy were low. None of the normal group has a low SP1 value. Conclusion: In routine testing, the value of blood serum SP1 in late pregnant women has important clinical significance.