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目的：探讨胺碘酮联合美托洛尔治疗老年冠心病并发心律失常的临床疗效。方法随机选取2013年3月至2014年3月于本院治疗老年冠心病并发心律失常患者143例，随机分为研究组72例，对照组71例。对照组患者予以胺碘酮治疗，研究组患者予以胺碘酮联合美托洛尔治疗，比较两组患者疗效指标和不良反应。结果治疗后研究组患者的心率、测定QT间期的离散度（QTd）均低于对照组，差异有统计学意义（P＜0.05）；两组患者不良反应比较差异无统计学意义（P＞0.05）。结论老年冠心病并发心律失常行胺碘酮联合美托洛尔治疗效果明显，且不会增加不良反应。“,”Objective To investigate the clinical effect of amiodarone combined with metoprolol in the treatment of elderly patients with coronary heart disease and arrhythmia.Methods 2013 March to 2014 March were randomly selected in our hospital for the treatment of elderly patients with coronary heart disease and arrhythmia in 143 patients, were randomly divided into study group 72 cases,control group 71 cases.The control group was given amiodarone treatment,the study group with amiodarone combined with metoprolol treatment,compared two groups of indicators of eficacy and adverse reaction.Results Heart rate,QTd index value of the study group after treatment were lower than the control group,the diference was statisticaly significant(P0.05).Conclusion Elderly coronary heart disease compli-cated by cardiac arrhythmia line efficacy of amiodarone combined with metoprolol significantly without increasing adverse efectse.