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目的:观察溪黄草与虎杖水煎剂配伍对大鼠的利胆作用。方法:采用十二指肠给药,进行胆总管插管术,观察溪黄草与虎杖水煎剂配伍对大鼠胆汁流量以及对胆汁成分的影响。结果:溪黄草水煎剂、虎杖水煎剂均明显增加大鼠胆汁流量(P<0.01);配伍组增加大鼠胆汁流量的作用远较溪黄草组和虎杖组明显(P<0.05),也显著降低胆汁中胆固醇和胆红素含量,增加胆汁酸含量。结论:溪黄草与虎杖水煎剂配伍有显著的利胆作用,优于单味中药的利胆作用,并对胆汁成分有一定影响。
Objective: To observe the choleretic effect of compatibility of Xihuangcao and Polygonum cuspidatum in rats. Methods: The duodenum was used for intubation of common bile duct. The effects of compatibility of Xihuangcao and Polygonum cuspidatum on bile flow and bile composition were observed. Results: Xihuangcao decoction and Polygonum cuspidatum decoction significantly increased the bile flow in rats (P <0.01). The effect of increasing the bile flow in the compatibility group was much better than that in the Huangcao and Polygonum cuspidatum groups (P <0.05) Significantly reduce bile cholesterol and bilirubin content, increase bile acid content. Conclusion: Xihuangcao and Polygonum cuspidatum decoction has a significant choleretic effect, which is superior to the choleretic effect of single Chinese herbs and has certain influence on the bile composition.