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以奎尼丁(Quinidine)为模板分子,合成奎尼丁分子印迹聚合物(MIP)。通过封管聚合法研究不同功能单体对奎尼丁分子印迹聚合物的影响,并运用Scatchard方程研究奎尼丁分子印迹聚合物选择吸附特性。以甲基丙烯酸(MAA)为功能单体合成的分子聚合物具有较高的选择吸附性,并且印迹聚合物大于非印迹聚合物的吸附量。奎尼丁印迹聚合物用于临床对奎尼丁的富集与检测有应用前景。
Quinidine was used as a template to synthesize quinidine molecularly imprinted polymer (MIP). The effects of different functional monomers on quinidine molecularly imprinted polymers were studied by means of tube sealing polymerization. The selective adsorption characteristics of quinidine molecularly imprinted polymers were also studied by Scatchard equation. Molecular polymers synthesized with methacrylic acid (MAA) as the functional monomer have higher selective adsorption, and the imprinted polymer is larger than that of the non-imprinted polymer. Quinidine imprinted polymer for the clinical application of quinidine enrichment and detection of the future.