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对80例充血性心力衰竭患者,入院时检测脑钠肽(BNP)水平,并行心脏彩色多普勒超声仪测定左心室射血分数(LVEF)、左室舒张末期内径(LVEDD)、左室短轴缩短率(FS)、左房内径(LAD)及胸部X线片测定心胸比例。结果:血浆脑钠肽(BNP)水平随着心功能纽约分级(NY-HA)程度的加重而显著增加,其与左室射血分数(LVEF)、左室短轴缩短率(FS)分别呈负相关,相关系数分别为r=-0.674(P<0.001)、r=-0.616(P<0.001);与左房内径(LAD)、左室舒张末期内径(LVEDD)分别呈正相关,相关系数分别为r=0.581(P<0.001)、r=0.582(P<0.001)。结论:充血性心力衰竭患者血浆BNP水平随着心力衰竭严重程度的增加而升高。血浆脑钠肽(BNP)水平的检测有利于充血性心力衰竭患者的早期诊断、病情评估,并能较好的反映心脏结构和功能。
In 80 patients with congestive heart failure, BNP levels were measured at admission and left ventricular ejection fraction Axial shortening (FS), left atrial diameter (LAD) and chest X-ray determination of cardiothoracic ratio. Results: The level of plasma brain natriuretic peptide (BNP) increased significantly with the increase of New York NY grade (NY-HA), which was correlated with left ventricular ejection fraction (LVEF) and left ventricular fractional shortening (FS) (P <0.001), r = -0.616 (P <0.001). The correlation coefficients were positively correlated with LAD and LVEDD, respectively, and the correlation coefficients were respectively R = 0.581 (P <0.001), r = 0.582 (P <0.001). Conclusions: BNP levels in patients with congestive heart failure increase with the severity of heart failure. The detection of plasma brain natriuretic peptide (BNP) is beneficial to the early diagnosis and assessment of patients with congestive heart failure, and can better reflect the structure and function of the heart.