论文部分内容阅读
血小板粘附,聚集和释放反应在血栓形成过程中起着重要作刚。血栓闭塞性脉管炎等瘀症疾病应用脉络宁(由玄参、牛膝等多种中药制成)治疗在临床上已获得良好疗效。为了探讨该中药复方制剂的某些活血化瘀机理,我们应用正常人及大白鼠血小板,观察了脉络宁对血小板聚集和释放内源性5—羟色胺(5一HT)的影响。材料与方法一、材料: 1. 脉络宁注射液:本所药物研究室供应,批号1984、1,每毫升含生药10克。 2. 血小板来源:取自本院10名健康成年职工及混合种大白鼠。
Platelet adhesion, aggregation and release reactions play an important role in the thrombogenesis process. Throat occlusive vasculitis and other snoring disease application Mailuoning (made of Scrophularia, Achyranthes and other Chinese medicines) treatment has been clinically good effect. In order to explore the mechanism of certain blood circulation of this Chinese herbal compound preparation, we used normal human and rat white blood platelets to observe the effect of Mailuoning on platelet aggregation and release of endogenous 5-HT (5-HT). Materials and Methods 1. Materials: 1. Mailuoning Injection: supplied by the Drug Research Laboratory of the Institute, batch number 1984, 1, containing 10 grams of crude drug per milliliter. 2. Platelet source: Taken from 10 healthy adult workers and mixed species rats in this hospital.