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目的总结乳腺颗粒细胞瘤临床误诊经验教训。方法回顾分析2例乳腺颗粒细胞瘤术前临床病理资料。结果 2例乳腺颗粒细胞瘤临床症状及体征无明显特殊性,镜下结构,细胞形态特殊,生长方式呈浸润性,免疫组化检查显示S-100、NSE(+),CEA(-)。结论乳腺颗粒细胞瘤较少见,临床、细胞学及冰冻、微波快速病理检查均易误诊为恶性肿瘤,应提高对此疾病的认识,提高对该病的术前病理诊断,减少不必要的扩大手术。
Objective To summarize the clinical misdiagnosis and experience of breast granulosa cell tumor. Methods Retrospective analysis of 2 cases of breast granulosa cell tumor preoperative clinical and pathological data. Results There were no obvious clinical symptoms and signs in 2 cases of breast granulosa cell tumor. The microstructure, cell morphology and infiltration of growth pattern were observed. Immunohistochemical examination revealed S-100, NSE (+) and CEA (-). Conclusion Breast granulocytoma is rare, clinical, cytology and frozen, microwave rapid pathological examination are easily misdiagnosed as malignant tumors, should raise awareness of the disease, improve the preoperative pathological diagnosis of the disease and reduce the unnecessary expansion surgery.