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观察多潘立酮(吗叮啉)治疗慢性胃炎改善消化不良症状及胃排空的疗效。对慢性胃炎患者采用开放随机对照试验,给予多潘立酮,并与莫沙比利对照进行疗效评估。结果对照组疗效与试验组比较除腹痛积分高于试验组(P<0.01)外,其他症状积分差异均无显著性。本文结果说明多潘立酮能明显改善慢性胃炎患者的消化不良症状和生活质量,其机制与协调胃运动,促进胃排空有关。
To observe the effect of domperidone (domperidone) in the treatment of chronic gastritis to improve dyspeptic symptoms and gastric emptying. An open-label randomized controlled trial of domperidone was given to patients with chronic gastritis and evaluated for efficacy with mosapride. Results Compared with the experimental group, the scores of other symptoms in the control group were not significantly different except the scores of abdominal pain were higher than those of the experimental group (P <0.01). The results show that domperidone can significantly improve the symptoms and quality of life of patients with chronic gastritis dyspepsia, its mechanism and coordination of gastric motility, and promote gastric emptying.