目的分析染色体的多态核型及其临床效应。方法对近五年本院的3721例有生殖异常患者进行外周血染色体核型分析。结果共检出染色体多态核型212例,检出率5.7%。这些患者均有不育、不良孕产史等临床表现。结论染色体多态性有一定的临床效应,临床应引起重视。 Objective To analyze the polymorphism of chromosomes and their clinical effects. Methods In the past five years, 3721 patients with genital abnormalities in our hospital were analyzed for karyotype of peripheral blood. Results A total of 212 cases of chromosome polymorphism were detected, the detection rate was 5.7%. These patients have infertility, poor history of pregnancy and other clinical manifestations. Conclusion Chromosome polymorphism has some clinical effects, clinical should pay attention.