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目的观察复方丹参滴丸治疗脑梗死的疗效。方法选取2012年1月—2013年1月易县医院收治的脑梗死患者98例,随机分为观察组与对照组,各49例。两组患者均予以基础治疗,对照组患者予以静脉注射依达拉奉注射液治疗,观察组患者在对照组基础上予以复方丹参滴丸治疗。观察两组患者治疗前与治疗后20d脑梗死体积和血浆同型半胱氨酸(Hcy)水平及治疗后6个月日常生活活动能力(ADL)分级。结果治疗前两组患者脑梗死体积和血浆Hcy水平比较,差异无统计学意义(P>0.05);治疗后20d观察组患者脑梗死体积小于对照组,血浆Hcy水平低于对照组(P<0.05);治疗后6个月观察组患者ADL分级优于对照组(P<0.05)。结论复方丹参滴丸治疗脑梗死的疗效显著,能有效减小脑梗死体积,降低血浆Hcy水平,改善患者ADL分级,提高患者生活质量。
Objective To observe the curative effect of Fufang Danshen Diwan on cerebral infarction. Methods From January 2012 to January 2013, 98 patients with cerebral infarction treated in Yixian Hospital were randomly divided into observation group and control group, with 49 cases in each group. Patients in both groups were given basic treatment. Patients in control group were treated with edaravone intravenously. Patients in observation group were given compound Danshen dropping pills on the basis of control group. The volume of cerebral infarction, plasma homocysteine level (Hcy) and the grading of daily living activity (ADL) of the two groups before treatment and 20 days after treatment were observed. Results There was no significant difference in cerebral infarction volume and plasma Hcy levels between the two groups before treatment (P> 0.05). After 20 days of treatment, the volume of cerebral infarction in the observation group was smaller than that in the control group, and plasma Hcy level was lower than that in the control group (P <0.05) ). ADL grade in observation group was better than control group in 6 months after treatment (P <0.05). Conclusion Compound Danshen Dripping Pill has significant curative effect on cerebral infarction. It can effectively reduce the volume of cerebral infarction, decrease the level of plasma Hcy, improve the grade of ADL, and improve the quality of life of patients.