羊水是胎儿在母体内生长发育的重要环境,通过羊水细胞培养及其核型分析可以在胎儿出生前准确的知道其性别和染色体组型是否异常以检测胎儿的某些遗传性疾病。早在1965年 Klinger 和 Macintyier 用羊水细胞进行核型分析获得成功;1966年 Steelo 和 B-reg 通过羊水细胞培养首先发表了关于胎儿 Amniotic fluid is an important environment for the fetus to grow and develop in the mother’s body. Through amniotic fluid cell culture and its karyotype analysis, amniotic fluid can accurately know whether the sex and chromosome constitution are abnormal before fetus birth to detect some genetic diseases of the fetus. As early as 1965, Klinger and Macintyier successfully performed karyotyping with amniotic fluid cells. In 1966, Steelo and B-reg first published fetal fibroblasts on amniotic fluid cell culture