FANCF蛋白表达在急性髓系白血病中的临床意义

来源 :白血病·淋巴瘤 | 被引量 : 0次 | 上传用户:mdskct
下载到本地 , 更方便阅读
声明 : 本文档内容版权归属内容提供方 , 如果您对本文有版权争议 , 可与客服联系进行内容授权或下架
论文部分内容阅读
目的 研究急性髓系白血病(AML)患者中FANCF蛋白的表达,探讨FANCF蛋白在AML中的意义.方法 以AML患者骨髓提取的单个核细胞为研究对象,采用Western blotting印迹法分析FANCF蛋白表达.结果 FANCF蛋白在初诊组表达为0.643±0.265,完伞缓解组表达为1.231±0.201,对照组表达为1.348±0.237;初诊AML组与对照组比较差异有统计学意义(P<0.05);FANCF蛋白表达完全缓解AML组与对照组比较差异无统计学意义(P>0.05).结论 FANCF 蛋白在初诊AML中表达下调,FA通路不能形成,可能与AML发病有相关性,与完全缓解AML组表达无明显变化,提示与AML预后有相关性.
其他文献
For two independent non-negative random variables X and Y, we treat X as the initial variable of major importance and Y as a modifier (such as the interest rate
Submerged vanes are submerged foils constructed in a river at an angle of attack to induce horizontal circulation in the downstream flow. The initial height of
Based on analyses of the share of documents of structural geology and tectonics in the GeoRef system over 100 years in the last century, and the historical chan
A zero-dimensional single-zone double-curve model is presented to predict fuel burning rate in stratified charge engines, and it is integrated with GT-Power to
The effect of coaxial, offset and extended inlet/outlet on the acoustic attenuation characteristics of circular expansion chambers are studied by the three-dime
Based on multi-body dynamics, the simulation models of auto-side structures and occupant’s dynamic responses are set up, using the occupant injury simulation s
本文基于网络技术飞速发展、大学生成为网络文化的重要群体的时代背景,结合网络的特点,分析了校园网在医学院校人文素质教育方面的优势,提出了医学院校要以互联网的普及为契
The multi-tone frequency modulation (FM) signal transferred through track circuit in automatic train control (ATC) system is analyzed. A digital filter with ide
荀子对语言的认识集中体现在《荀子·正名》中。《正名》涉及语言的本质、产生、特征与创新等诸多问题,其中对语言学的论述对今天语言研究仍有重要的指导意义。 Xunzi’s un
本文对影响跨文化交际的四个易被忽视的“盲区”进行了认真的剖析,论述了西方文化特征和中西方文化交流障碍,认为跨文化交际者只有充分理解迥异的中西方文化,掌握迥异的英汉