论文部分内容阅读
目的:探讨强直性脊柱炎患者血沉(ESR)、C-反应蛋白(CRP)水平与脊柱活动度的关系,为强直性脊柱炎的治疗提供参考。方法:收集129例临床诊断为AS的患者,测定血沉、C-反应蛋白水平,并测量腰椎前屈和后伸活动度、指地距、胸廓活动度、Schober结果试验,运用Pearson相关分析方法进行统计分析。结果:前屈和后伸活动度、Schober试验结果与CRP水平呈负相关关系(P<0.05),前屈活动度、胸廓活动度、Schober试验结果与ESR水平呈负相关关系(P<0.05),指地距与ESR和CRP水平均无显著相关性(P>0.05)。结论:ESR和CRP的升高可以在一定程度上反映AS患者腰椎、胸椎活动度下降,建议临床上综合考虑,对于出现ESR和CRP水平升高明显者重视髋关节、腰椎、胸廓的功能锻炼。
Objective: To investigate the relationship between ESR and C-reactive protein (CRP) level and spine activity in patients with ankylosing spondylitis, and provide references for the treatment of ankylosing spondylitis. Methods: A total of 129 patients with clinically diagnosed AS were enrolled in this study. The ESR and C-reactive protein levels were measured. The lumbar flexion and extension activities, the mean distance between the anterior and posterior lumbar vertebrae, and the Schober test were measured. Pearson correlation analysis Statistical Analysis. Results: There was a negative correlation between Schober test result and CRP level (P <0.05), flexion activity, thoracic activity, Schober test result and ESR level (P <0.05) There was no significant correlation between ESR and CRP levels (P> 0.05). CONCLUSIONS: Elevated ESR and CRP may reflect the degree of lumbar spine and thoracic vertebral movements in AS patients to a certain extent. It is suggested that they should be taken into consideration clinically. Functional exercise of hip joint, lumbar spine and thorax should be emphasized in patients with obvious increase of ESR and CRP.