皮质类固醇类药物(通常指地塞米松)应用于各种类型的脑膜炎,但是令人信服的效果仅限于脑水肿伴有占位病损.例如,类固醇类药物已广泛用于脑性疟疾作为急救药物,但最近通过Warrell等的双盲试验证实这种治疗不仅无益,反而使昏迷期延长,并容易发生肺炎,而且明显加剧胃肠道出血. Corticosteroids, commonly referred to as dexamethasone, are used in all types of meningitis, but the convincing effect is limited to cerebral edema with space-occupying lesions. For example, steroids have been widely used in cerebral malaria as First-aid drugs, but recent double-blind trials by Warrell et al. Confirmed that this treatment was not only useless, but rather prolonged coma, and prone to pneumonia, but also significantly exacerbated gastrointestinal bleeding.