目的分析配合型输血与同型输血对患者红细胞不规则抗体产生的影响。方法回顾性分析本院2014年5月—2016年5月输血治疗的400例患者临床资料,将因特殊情况实施ABO、Rh D配合型输血的200例患者设为观察组,将同型输血的200例患者设为对照组,比较2组输血后对红细胞不规则抗体产生的影响。结果观察组红细胞不规则抗体阳性检出率4.5%、不良输血反应发生率3%,同期对照组红细胞不规则抗体阳性检出率7%、不良输血反应发生率4%,差异无统计学意义(P>0.05);2组输血有效性比较差异无统计学意义(P>0.05)。结论同等有效性的前提下配合型输血红细胞不规则抗体阳性检出率及不良输血反应发生率相较于同型输血更低,为当前临床输血治疗方案的最佳选择。 Objective To analyze the effect of combined blood transfusion and blood transfusion on irregular erythrocyte antibody in patients. Methods The clinical data of 400 patients transfused from May 2014 to May 2016 in our hospital were retrospectively analyzed. 200 patients who underwent special blood transfusion with ABO and Rh D were enrolled in the observation group. The 200 The patients were set as the control group, comparing the two groups of blood transfusion of irregular antibodies on the impact of red blood cells. Results In the observation group, the positive rate of RBC irregular antibody was 4.5% and the incidence of adverse transfusion reaction was 3%. In the same period, the positive rate of RBC irregular antibody in control group was 7%, and the incidence of adverse transfusion reaction was 4%. There was no significant difference P> 0.05). There was no significant difference in the effectiveness of blood transfusion between the two groups (P> 0.05). Conclusions The positive detection rate of irregular transfusion red blood cell antibodies and the incidence of adverse transfusion reactions are lower than those of the same transfusion under the same validity. It is the best choice for the current clinical transfusion therapy.