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目的探讨树突状细胞调节细胞因子诱导杀伤细胞(DC-CIK)配合中药治疗化疗无效晚期恶性肿瘤的临床疗效。方法选取2012年2月至2013年2月间采用DC-CIK配合中药治疗化疗无效的晚期恶性肿瘤患者120例,观察评价其近期疗效,生活质量改善情况及不良作用。结果 120例患者中,临床有效率为12.5%,疾病控制率为69.2%。治疗后,患者生活质量明显改善,治疗过程中未发生明显不良反应。结论 DC-CIK细胞因子配合中药治疗化疗无效的晚期恶性肿瘤是一种有效的姑息治疗方法,有必要进行深入的临床研究。
Objective To investigate the clinical effect of dendritic cells regulating cytokine-induced killer cells (DC-CIK) combined with traditional Chinese medicine in the treatment of chemotherapy-refractory advanced malignant tumors. Methods From February 2012 to February 2013, 120 patients with advanced malignant tumor who were treated with chemotherapy with DC-CIK and Chinese herbs were selected and evaluated for their short-term curative effect, quality of life improvement and adverse effects. Results Among the 120 patients, the clinical effective rate was 12.5% and the disease control rate was 69.2%. After treatment, the quality of life of patients improved significantly, no significant adverse reactions during treatment. Conclusion DC-CIK cytokines combined with traditional Chinese medicine in the treatment of chemotherapy-refractory advanced malignancies is an effective palliative treatment, it is necessary to conduct in-depth clinical studies.