绪言在先天性和后天性耳聋的病因学中,氨基糖甙类抗生素已显出普遍的内耳毒性。由于新的耳毒性氨基糖甙类抗生素不断问世,应用日广,加之临床上对此类药物的毒害作用认识不足,滥用现象严重,致使此类药物所引起的内耳中毒性耳聋患者不断增多,特 Introduction In the etiology of congenital and acquired deafness, aminoglycoside antibiotics have shown widespread inner ear toxicity. As the new ototoxic aminoglycoside antibiotics continue to come out, the wide application, combined with the clinical lack of knowledge of the toxic effects of such drugs, abuse serious, resulting in such drugs caused by the increase in patients with deafness of the inner ear toxicity, especially