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纳洛酮(Naloxone)是一种竞争性纯阿片受体拮抗剂,用于吗啡类复合麻醉药术后解除呼吸抑制及催醒作用。自1981年Baskin等首次报道纳洛酮能改善脑缺血病人的神经功能损害症状后,很受人们重视。我院自1995年来对住院的脑梗死病人,应用纳洛酮治疗,取得了显著的疗效。1 临床资料1.1 病例分组按入院先后顺序将脑梗死住院病人分为3组:纳洛酮A组、纳洛酮B组和普通治疗组。全部病人均经头颅CT扫描确诊。纳洛酮A组42例,发病时间在24小时以内,其中男34例,女8例,平均
Naloxone is a competitive, pure opioid receptor antagonist used to relieve respiratory depression and wake-up after a morphine-based combination anesthetic. Since 1981, Baskin et al first reported that naloxone can improve the symptoms of neurological damage in patients with cerebral ischemia, very much attention. Our hospital since 1995 to hospitalized patients with cerebral infarction, the application of naloxone treatment, and achieved remarkable results. 1 Clinical data 1.1 Case group according to the hospital admission sequence of cerebral infarction inpatients were divided into 3 groups: naloxone group A, naloxone B group and the general treatment group. All patients were diagnosed by head CT scan. Naloxone group A 42 cases, the onset time within 24 hours, including 34 males and 8 females, with an average