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[目的]分析福建省2006-2008年从发热病人中检出的登革热病例,提高监测水平。[方法]对福州、莆田、泉州和宁德等地送检的发热待查病人的血清标本372人份,用ELISA法检测登革热病毒IgM和IgG抗体,阳性标本进行病毒核酸检测和型别判定。[结果]IgM阳性率8.3%,IgG阳性率5.9%,其中IgM和IgG均阳性占5.6%,32份阳性标本中,19份检测出病毒核酸阳性,型别测定为登革Ⅰ型4份,登革Ⅱ型9份,登革Ⅲ型5份。经流行病学调查与实验室检测,确定32例为登革热病人,阳性率8.6%(32/372)。[结论]32例登革热,31例为输入性,1例为二代病例,并因此发现一起登革热暴发疫情。在登革热监测中,对发热待查者,应注意询问流行病学史和当地短期内有否出现大量高热、头痛和皮疹者,以及时准确发现病例。
[Objective] To analyze the cases of dengue fever detected in febrile patients in Fujian Province from 2006 to 2008, and to improve the monitoring level. [Method] A total of 372 serum specimens from fever patients to be investigated in Fuzhou, Putian, Quanzhou and Ningde were detected by ELISA for IgM and IgG antibodies against dengue virus. Positive samples were tested for virus nucleic acid and genotype. [Results] The positive rate of IgM was 8.3% and the positive rate of IgG was 5.9%. Positive IgM and IgG were 5.6%, of the 32 positive samples, 19 were positive for virus nucleic acid, 4 were Dengue type Ⅰ, Dengue type Ⅱ 9, Dengue Ⅲ type 5 copies. After epidemiological investigation and laboratory tests, 32 cases were confirmed as dengue fever patients, the positive rate was 8.6% (32/372). [Conclusion] There were 32 cases of dengue fever, 31 cases were imported, and 1 case was the second generation, so we found a dengue outbreak. In the monitoring of dengue fever, fever checker should pay attention to ask the epidemiological history and the local short-term whether there is a large number of high fever, headache and rash who timely and accurate detection of cases.